Overview
iDose TR (travoprost intracameral implant) is a sustained-release prostaglandin analog implant indicated for the reduction of intraocular pressure in patients with open-angle glaucoma or ocular hypertension. It provides continuous drug delivery directly into the anterior chamber, offering an alternative to daily topical eye drops.
Mechanism of Action
Travoprost is a synthetic prostaglandin F2α analog that reduces intraocular pressure by increasing uveoscleral outflow of aqueous humor through prostaglandin receptor activation in the ciliary muscle.
Indications
- Reduction of intraocular pressure in patients with open-angle glaucoma
- Reduction of intraocular pressure in patients with ocular hypertension
Common Doses
- Single intracameral implant (providing sustained travoprost release)
Dosage
Single intracameral implant administered by a healthcare professional during a minor surgical procedure. The implant provides sustained travoprost release for approximately 6 months.
Contraindications
- Active or suspected ocular or periocular infections
- Corneal endothelial dystrophy
- Prior corneal transplantation
- Hypersensitivity to travoprost or any component of the formulation
Side Effects
- Device dislocation
- Macular edema
- Intraocular inflammation
- Increased iris pigmentation
- Endophthalmitis
- Ocular hyperemia
- Eye pain
- Foreign body sensation
- Visual disturbances
Interactions
- No specific drug-drug interactions identified for the intracameral implant formulation. As a prostaglandin analog, theoretical interactions with other ocular hypotensive agents may occur when used concomitantly.
Counseling Points
- This is an implant placed inside the eye during a minor surgical procedure
- Regular follow-up visits are essential to monitor intraocular pressure and implant position
- Report any signs of infection, increased eye redness, pain, or vision changes immediately
- The implant provides continuous medication release for approximately 6 months
- Continue all other prescribed medications unless instructed otherwise by your ophthalmologist