Overview
Simethicone is an antiflatulent medication used to relieve symptoms of gas such as bloating, pressure, and fullness. It works by reducing surface tension of gas bubbles in the gastrointestinal tract, allowing them to coalesce and be expelled more easily. It is available over-the-counter and is generally considered safe with minimal systemic absorption.
Mechanism of Action
Simethicone is a surfactant that lowers the surface tension of gas bubbles in the gastrointestinal tract, causing them to coalesce into larger bubbles. This facilitates their elimination through belching or passing flatus, providing symptomatic relief from gas-related discomfort.
Indications
- Relief of pressure, bloating, and fullness commonly referred to as gas
Common Doses
- Extra strength formulation (specific strength not provided in source)
Dosage
Adults and children 12 years and older: Swallow 1 or 2 softgels with water as needed after meals and at bedtime. Do not exceed 4 softgels in 24 hours except under the advice and supervision of a physician.
Contraindications
- Known hypersensitivity to simethicone or any component of the formulation
Side Effects
- Generally well-tolerated with minimal side effects
- Rare allergic reactions may occur
Interactions
- No clinically significant drug interactions have been reported with simethicone
Counseling Points
- Take after meals and at bedtime as needed for gas symptoms
- Do not exceed recommended dosage
- Swallow whole with water
- Consult healthcare provider if symptoms persist beyond 7 days