Overview
Policresulen is a topical antiseptic and astringent agent used primarily for gynecological conditions. It exerts local antimicrobial and coagulative effects on damaged tissues, promoting hemostasis and wound healing in vaginal applications.
Mechanism of Action
Policresulen acts as a protein coagulant that denatures proteins in damaged tissues and microorganisms, creating a protective layer that controls bleeding, reduces inflammation, and exhibits antiseptic properties against bacteria and fungi.
Indications
- Vaginal infections and inflammations
- Cervical erosion (ectropion)
- Post-procedural wound care in gynecological surgery
- Symptomatic relief of vaginal discharge and irritation
Common Doses
- 90 mg suppository
- Typically one suppository daily
Dosage
Typically administered as one vaginal suppository daily, usually at bedtime, for 6-12 days as directed by a healthcare provider. Treatment duration may vary based on condition severity and response.
Contraindications
- Hypersensitivity to policresulen or any component
- Active vaginal bleeding of unknown origin
- Pregnancy (especially first trimester)
- Severe renal or hepatic impairment
Side Effects
- Local burning or irritation
- Vaginal discomfort or itching
- Increased vaginal discharge
- Rare allergic reactions
- Possible staining of clothing or linens
Interactions
- May interact with other vaginal products - avoid concurrent use
- Potential reduced efficacy with alkaline substances
- No significant systemic drug interactions documented
Counseling Points
- Use exactly as prescribed, typically at bedtime
- Insert suppository high into vagina using applicator or finger
- Use sanitary pad to protect clothing from discharge
- Complete full course even if symptoms improve
- Avoid tampons during treatment
- Report severe irritation or unusual symptoms