Nickel Sulfate, Potassium Bromide, And Fumaric Acid

Brand Names: Psorizide Forte

Drug Class: General Prescription

Overview

DESCRIPTION PSORIZIDE ® Forte is a biochemical homeopathic medication indicated for the treatment of contact dermatitis due to nickel (metal/jewelry allergy), dyshidrotic hand/foot eczema, and mild to severe psoriasis . 1-3 The active ingredients in each PSORIZIDE ® Forte tablet consist of the following: Fumaric Acid (Fumaricum Acidum) 1X, Potassium Bromide (Kali Bromatum) 1X, and Nickel Sulphate...

Mechanism of Action

CLINICAL PHARMACOLOGY The active ingredients in PSORIZIDE ® Forte are simple biochemical compounds. The exact mechanism of action is unknown; however, it is believed PSORIZIDE ® Forte addresses a primary genetic biochemical defect. 5 FUMARIC ACID is a naturally occurring four carbon organic acid important in the Krebs cycle. This biochemical pathway is of central importance to energy production. Each tablet contains approximately 30 mg fumaric acid (calculated). Fumaric Acid has many uses, including use as a food additive (GRAS) and as a chelating agent. 13 The use of fumaric acid and its derivatives (esters) as a treatment for psoriasis is increasing worldwide.

Indications

  • INDICATIONS PSORIZIDE ® Forte is indicated for the treatment of contact dermatitis due to nickel (metal/jewelry allergy,) dyshidrotic hand/foot eczema, and mild to severe psoriasis. It has been found to work well with a variety of combination therapies. Eczema, seborrhea and a variety of chronic pruritic inflammatory dermatoses generally respond well also.

Common Doses

  • 60 mcg

Dosage

DOSAGE AND ADMINISTRATION Absorption of nickel sulphate is variable among individuals . For maximum absorption, tablets should be taken orally at the beginning of the day (or any convenient time after having taken nothing but water for at least 7 hours). Take nothing but water for one hour after taking medication to aid absorption. Weight Starting Dose Max Daily Dose 40-80 lbs ½ tablet 1 ½ tablet 80-120 lbs 1 tablet 3 tablets 120-160 lbs 1 ½ tablets 4 ½ tablets 160-200 lbs 2 tablets 6 tablets 200-240 lbs 2 ½ tablets 7 ½ tablets Over 240 lbs 3 tablets 9 tablets In the setting of renal...

Contraindications

  • CONTRAINDICATIONS Although there are no known contraindications, patients who are allergic to any PSORIZIDE ® Forte ingredient should consult a physician prior to taking the medication. (Refer to Section on Hypersensitivity )

Side Effects

  • ADVERSE REACTIONS PSORIZIDE ® Forte contains low doses of active ingredients. Therefore there are minimal known side effects. (see PRECAUTIONS for hypersensitivity information)

Interactions

  • Drug Interactions There are no known drug interactions.