Overview
Description L-Arginine HCl Injection is a sterile, nonpyrogenic, hypertonic injectable solution containing 100 mg/mL of L-Arginine Hydrochloride in Sterile Water for Injection. The formulation contains benzyl alcohol 2% as a preservative, with pH adjusted to 5.0–6.5 using Hydrochloric Acid and/or Sodium Hydroxide.
Mechanism of Action
Description L-Arginine HCl Injection is a sterile, nonpyrogenic, hypertonic injectable solution containing 100 mg/mL of L-Arginine Hydrochloride in Sterile Water for Injection. The formulation contains benzyl alcohol 2% as a preservative, with pH adjusted to 5.0–6.5 using Hydrochloric Acid and/or Sodium Hydroxide. Each mL contains: L-Arginine HCl 100 mg Benzyl Alcohol 2% Sterile Water for Injection q.s. The solution is supplied as a multiple-dose vial for intravenous administration by a licensed healthcare professional. The calculated osmolarity is approximately 1148 mOsm/L. L-Arginine is an amino acid involved in multiple metabolic and physiologic pathways, including nitric oxide synthesis and nitrogen metabolism.
Common Doses
- Refer to label
Dosage
Refer to FDA label for detailed dosing.
Contraindications
- Contraindications L-Arginine HCl Injection is contraindicated in: Patients with known hypersensitivity to L-Arginine, benzyl alcohol, or any component of the formulation. Neonates, premature infants, or low birth weight infants due to the risk of benzyl alcohol toxicity (“gasping syndrome”). Patients with severe metabolic acidosis or conditions where administration of hypertonic solutions may worsen fluid or electrolyte imbalance. Patients with severe renal impairment or anuria unless clinically justified and closely monitored by a healthcare professional.
Interactions
- No major interactions listed on the FDA label. Always consult a healthcare professional.