Overview
Bisacodyl is a stimulant laxative used for the relief of occasional constipation. It works by directly stimulating colonic peristalsis, typically producing a bowel movement within 6 to 12 hours after administration. It is available over-the-counter and by prescription in various formulations.
Mechanism of Action
Bisacodyl is a contact stimulant laxative that acts directly on the colonic mucosa to stimulate sensory nerve endings, increasing intestinal motility and promoting peristalsis. It also enhances fluid and electrolyte secretion into the colon, softening stool and facilitating evacuation.
Indications
- Relief of occasional constipation
- Management of irregularity
- Bowel preparation prior to medical procedures (as directed)
Common Doses
- 5 mg capsule
- 10 mg tablet
- 10 mg suppository
Dosage
Adults and children 12 years and older: Start with 1 capsule (5 mg) daily, taken with a full glass of water. May increase to 2-3 capsules (10-15 mg) daily as a single dose if needed. Children 6-12 years: 1 capsule (5 mg) daily. Children under 6 years: Consult physician.
Contraindications
- Hypersensitivity to bisacodyl or any component
- Acute surgical abdomen
- Intestinal obstruction
- Acute inflammatory bowel disease
- Severe abdominal pain with nausea and vomiting
Side Effects
- Abdominal discomfort or cramping
- Nausea
- Diarrhea
- Electrolyte disturbances with prolonged use
- Rectal irritation
- Weakness or dizziness
Interactions
- Antacids and dairy products may decrease effectiveness if taken within 1 hour
- Diuretics may increase risk of electrolyte imbalance
- May reduce absorption of other oral medications if taken concurrently
Counseling Points
- Take with a full glass of water
- Do not chew or crush capsules
- Typically produces bowel movement in 6-12 hours
- Best taken at bedtime for morning results
- Do not use for more than 7 days without medical advice
- Maintain adequate fluid intake
- Increase dietary fiber for long-term constipation management